Bacterial Resistance: Understanding the Threat
This worksheet explores bacterial resistance, its causes, mechanisms, and consequences, suitable for Grade 10 Science students.
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Bacterial Resistance: Understanding the Threat
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Read each question carefully and answer to the best of your ability. Use complete sentences for short answer questions.
Bacterial resistance, also known as antibiotic resistance, is a growing global health concern. It occurs when bacteria evolve and become tolerant to antibiotics, making infections harder to treat. This section will introduce you to the basics of bacterial resistance.

1. What is the primary cause of bacterial resistance?
Overuse of vaccines
Misuse and overuse of antibiotics
Lack of proper hygiene
Genetic engineering in bacteria
2. Which of the following is NOT a mechanism by which bacteria can become resistant to antibiotics?
Mutation in bacterial DNA
Horizontal gene transfer
Increased bacterial reproduction rate
Efflux pumps actively removing antibiotics
3. Bacterial resistance is a form of where bacteria adapt to survive in the presence of antibiotics.
4. The transfer of genetic material between bacteria, leading to resistance, is called gene transfer.
5. A common example of an antibiotic-resistant bacterium often found in hospitals is .
6. Taking antibiotics for viral infections helps prevent bacterial resistance.
True
False
7. Completing the full course of antibiotics, even if you feel better, is crucial to minimize resistance.
True
False
8. Explain how natural selection contributes to the development of antibiotic resistance in bacteria.
9. Describe two ways in which humans can help prevent the spread of antibiotic resistance.
Use the words below to complete the sentences.
10. Bacteria can acquire resistance through random changes in their DNA, known as a .
11. Small, circular pieces of DNA called can carry resistance genes and be transferred between bacteria.
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