Mass Spectrometry Fundamentals
This worksheet introduces students to the basic principles and applications of mass spectrometry, including ionization, mass analyzer, and detector.
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Standards
Topics
Mass Spectrometry Fundamentals
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Read each question carefully and answer to the best of your ability. Show all your work where applicable.
1. Which of the following is NOT a main component of a mass spectrometer?
Ionization source
Mass analyzer
Refractometer
Detector
2. What is the primary purpose of the ionization source in mass spectrometry?
To separate ions by mass
To convert neutral molecules into ions
To detect the ions
To create a vacuum
1. In mass spectrometry, the ratio of mass to charge is represented as .
2. The separates ions based on their mass-to-charge ratio.
3. A mass spectrum typically plots against mass-to-charge ratio.
1. Mass spectrometry can be used to determine the molecular weight of a compound.
True
False
2. All mass spectrometers operate under high vacuum conditions.
True
False
1. Briefly describe the three main stages of a mass spectrometry experiment.
2. Explain why a vacuum is necessary for the operation of a mass spectrometer.
Match each term with its correct description.
1. Ionization
a. Measures the abundance of ions
2. Mass Analyzer
b. Converts molecules into charged particles
3. Detector
c. Separates ions by mass-to-charge ratio