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Thin Layer Chromatography (TLC) Worksheet

Grade 11 Chemistry worksheet on Thin Layer Chromatography covering principles, applications, and calculations.

Grade 11 Science ChemistryThin Layer Chromatography
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TextMultiple ChoiceShort AnswerFill in the BlanksCustomTrue / False

Standards

HS-PS1-3HS-PS1-7

Topics

chemistrychromatographyTLCseparation techniquesgrade 11
8 sections · Free to use · Printable
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Thin Layer Chromatography (TLC) Worksheet

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Read each question carefully and provide your answers in the space provided. For multiple-choice questions, circle the correct option. For calculations, show all your work.

Thin Layer Chromatography (TLC) is a widely used analytical technique for separating non-volatile mixtures. It is a quick, inexpensive, and simple method to monitor the progress of reactions, identify compounds present in a given substance, and determine the purity of a substance.

1. Which of the following is the stationary phase in Thin Layer Chromatography?

a

Solvent

b

Mobile phase

c

Adsorbent coated plate

d

Analyte

2. What is the primary principle behind the separation of compounds in TLC?

a

Boiling point differences

b

Differences in solubility and adsorption

c

Molecular weight differences

d

Density differences

3. Briefly explain the role of the mobile phase in TLC.

4. List two common applications of Thin Layer Chromatography in a chemistry laboratory.

5. The distance traveled by a compound relative to the solvent front is known as the   factor.

6. A TLC plate is typically made of a solid support (like glass, plastic, or aluminum foil) coated with a thin layer of   material.

Refer to the diagram below showing a typical Thin Layer Chromatography setup.

Chromatography Setup

7. In a TLC experiment, compound X traveled 4.5 cm from the origin, and the solvent front traveled 9.0 cm. Calculate the Rf value for compound X. Show your work.

8. A higher Rf value indicates that the compound has a stronger interaction with the stationary phase.

T

True

F

False