Bacterial Resistance Worksheet
Explore bacterial resistance mechanisms, causes, and impacts on public health with this Grade 12 Biology worksheet.
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Standards
Topics
Bacterial Resistance: A Global Challenge
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Read each question carefully and provide thoughtful, detailed answers. Use complete sentences and scientific terminology where appropriate.
1. Which of the following is NOT a common mechanism of antibiotic resistance in bacteria?
Enzymatic degradation of the antibiotic.
Increased permeability of the bacterial cell membrane to the antibiotic.
Efflux pumps actively expelling the antibiotic.
Modification of the antibiotic target site.
2. The transfer of genetic material between bacteria via a bacteriophage is known as:
Conjugation
Transformation
Transduction
Mutation
3. The overuse and misuse of is a primary driver of antibiotic resistance.
4. Bacteria can share resistance genes through horizontal gene transfer mechanisms such as conjugation, transformation, and .
5. Briefly explain the concept of natural selection in the context of bacterial resistance to antibiotics.
6. Describe one significant public health consequence of widespread antibiotic resistance.
7. All bacteria are harmful and cause disease.
True
False
8. Handwashing is an effective method to prevent the spread of antibiotic-resistant bacteria.
True
False
9. Examine the diagram of a bacterial cell below. Identify and label two structures that could be targets for antibiotic action.

10. Discuss the ethical considerations associated with the development and use of new antibiotics, particularly in the context of preventing further antibiotic resistance.