Grade 12 Biology Principles Worksheet
This worksheet covers fundamental concepts in Grade 12 Biology Principles, including DNA structure, genetics, and cellular processes.
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Grade 12 Biology Principles
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Read each question carefully and answer to the best of your ability. Show all work for calculations.
1. Which of the following best describes the structure of a DNA molecule?
Single-stranded helix
Double-stranded parallel structure
Double-stranded helix
Triple-stranded helix
2. Which organelle is primarily responsible for ATP production in eukaryotic cells?
Nucleus
Mitochondria
Ribosome
Endoplasmic Reticulum

3. The two strands of a DNA molecule are held together by bonds between complementary nitrogenous bases.
4. In DNA, adenine always pairs with , and guanine always pairs with .
5. All living organisms use DNA as their genetic material.
True
False
6. Meiosis results in four genetically identical daughter cells.
True
False
7. Briefly explain the central dogma of molecular biology.
8. Describe the main differences between prokaryotic and eukaryotic cells.
Match each term on the left with its definition on the right.
9. Gene
a. The process of copying DNA
10. Allele
b. A segment of DNA that codes for a protein
11. Replication
c. Different forms of a gene
12. Transcription
d. Synthesis of RNA from a DNA template