Grade 12 Blood Typing Worksheet
A comprehensive worksheet for Grade 12 Biology students on blood typing, including ABO and Rh systems, compatibility, and genetic inheritance.
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Topics
Blood Typing: ABO and Rh Systems
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Read each question carefully and provide concise answers based on your understanding of human blood typing. Show all your work for genetic crosses.
1. Which of the following blood types is considered the 'universal donor'?
Type A+
Type B-
Type O-
Type AB+
2. What antigens are present on the red blood cells of an individual with Type AB blood?
A antigens only
B antigens only
Both A and B antigens
Neither A nor B antigens
3. The presence or absence of the Rh factor determines whether a blood type is or negative.
4. Agglutination, or the clumping of red blood cells, occurs when bind to specific antigens on the red blood cell surface.
5. Explain why a person with Type O blood can only receive blood from another Type O individual, but can donate to all ABO blood types.
6. Below is an illustration of different blood cells. Identify the primary cell type responsible for carrying oxygen and briefly describe its characteristics relevant to blood typing.

7. A person with Type O- blood can safely receive a transfusion from a donor with Type A+ blood.
True
False
8. A man with heterozygous Type A blood (I^A i) and a woman with Type AB blood (I^A I^B) are expecting a child. Using a Punnett square, determine the possible genotypes and phenotypes of their offspring, and the probability of each.