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Citric Acid Cycle Worksheet

Grade 12 Biology worksheet covering the Citric Acid Cycle (Krebs Cycle), including its steps, products, and role in cellular respiration.

Grade 12 Science BiologyCitric Acid Cycle
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Includes

Multiple ChoiceFill in the BlanksTrue / FalseShort AnswerMatching

Standards

NGSS.HS-LS1-7

Topics

BiologyCitric Acid CycleKrebs CycleCellular RespirationGrade 12
7 sections · Free to use · Printable
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Citric Acid Cycle Worksheet

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Read each question carefully and answer to the best of your ability. Show all your work where applicable.

1. The Citric Acid Cycle occurs in which part of the eukaryotic cell?

a

Cytoplasm

b

Inner mitochondrial membrane

c

Mitochondrial matrix

d

Outer mitochondrial membrane

2. What molecule enters the Citric Acid Cycle by combining with oxaloacetate?

a

Pyruvate

b

Acetyl-CoA

c

Glucose

d

Citrate

1. For each molecule of acetyl-CoA that enters the Citric Acid Cycle,   molecules of CO2 are released.

2. The primary role of the Citric Acid Cycle is to produce high-energy electron carriers such as   and  .

1. The Citric Acid Cycle is an anaerobic process.

T

True

F

False

2. GTP is produced directly in the Citric Acid Cycle and can be converted to ATP.

T

True

F

False

1. Briefly explain the significance of the Citric Acid Cycle in cellular respiration.

2. What are the key products generated by the Citric Acid Cycle that will proceed to the electron transport chain?

Match each molecule with its role in the Citric Acid Cycle.

1. Acetyl-CoA

 

a. Final electron acceptor

2. Oxaloacetate

 

b. Enters the cycle by combining with oxaloacetate

3. Citrate

 

c. Regenerated at the end of the cycle

4. NADH/FADH2

 

d. First molecule formed in the cycle