DNA Replication Worksheet
A Grade 12 science worksheet covering the process of DNA replication, including key enzymes, steps, and related concepts.
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DNA Replication Worksheet
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Read each question carefully and answer to the best of your ability. Refer to your notes or textbook if needed.
1. Which enzyme is responsible for unwinding the DNA double helix during replication?
DNA Polymerase
Helicase
Ligase
Primase
2. Okazaki fragments are found on which strand during DNA replication?
Leading strand
Lagging strand
Both strands
Neither strand
3. DNA replication is described as , meaning each new DNA molecule consists of one original strand and one newly synthesized strand.
4. The enzyme synthesizes new DNA strands by adding nucleotides complementary to the template strand.
5. The short RNA primer is synthesized by the enzyme .
6. Describe the role of DNA ligase in DNA replication.
7. Observe the diagram of a DNA replication fork below and answer the questions that follow.
a) Identify the leading strand and the lagging strand in the diagram.
b) Explain why the lagging strand is synthesized discontinuously.
8. DNA replication occurs during the G1 phase of the cell cycle.
True
False
9. Topoisomerase prevents supercoiling of the DNA ahead of the replication fork.
True
False