DNA Structure and Function Worksheet
Grade 12 Science worksheet covering the structure, replication, and function of DNA.
Includes
Standards
Topics
DNA Structure and Function
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Read each question carefully and answer to the best of your ability. Show all work where applicable.
1. Which of the following best describes the structure of a DNA molecule?
A single-stranded helix
A double helix with parallel strands
A double helix with antiparallel strands
A triple helix
2. Which enzyme is responsible for unwinding the DNA double helix during replication?
DNA Polymerase
Ligase
Helicase
Primase
3. The two strands of DNA are held together by bonds between complementary nitrogenous bases.
4. DNA replication is described as , meaning each new DNA molecule consists of one original strand and one newly synthesized strand.
5. Describe the key components of a DNA nucleotide.

6. Based on the image of the DNA double helix, explain Chargaff's rules regarding base pairing.
7. RNA contains deoxyribose sugar, while DNA contains ribose sugar.
True
False
Match each term on the left with its correct definition on the right.
8. Transcription
a. Synthesis of a polypeptide chain from mRNA
9. Translation
b. Process of copying DNA into RNA
10. Codon
c. A three-nucleotide sequence that codes for an amino acid