Endocrine System Worksheet
A Grade 12 science worksheet covering the human endocrine system, hormones, glands, and their functions.
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Endocrine System Worksheet
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Read each question carefully and answer to the best of your ability. For multiple-choice questions, select the best option. For fill-in-the-blank and short-answer questions, write your response in the space provided.
1. Which of the following is NOT an endocrine gland?
Thyroid gland
Salivary gland
Adrenal gland
Pituitary gland
2. Which hormone is responsible for regulating blood sugar levels?
Thyroxine
Estrogen
Insulin
Testosterone
3. The gland is often referred to as the 'master gland' because it controls several other hormone glands.
4. Hormones are chemical messengers produced by endocrine glands and transported through the .
5. The 'fight or flight' response is primarily mediated by hormones released from the glands.
6. Describe the main difference between exocrine and endocrine glands.
7. Label the major endocrine glands in the diagram below:

8. The pancreas has both endocrine and exocrine functions.
True
False
9. All hormones are protein-based molecules.
True
False
Match the hormone with its primary function.
10. Adrenaline
a. Regulates metabolism
11. Thyroxine
b. Stimulates 'fight or flight' response
12. Oxytocin
c. Influences sleep-wake cycles
13. Melatonin
d. Involved in social bonding and childbirth