Grade 12 Biology: Nucleic Acids Worksheet
This worksheet covers the structure, function, and types of nucleic acids (DNA and RNA) for Grade 12 Biology students.
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Standards
Topics
Nucleic Acids: Structure and Function
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Read each question carefully and answer to the best of your ability. Use complete sentences for short answer questions.
1. Which of the following is NOT a component of a nucleotide?
Phosphate group
Pentose sugar
Amino acid
Nitrogenous base
2. What type of bond connects the complementary base pairs in a DNA molecule?
Covalent bond
Ionic bond
Hydrogen bond
Peptide bond
1. DNA is a polymer made of repeating units called .
2. The two strands of DNA are held together by bonds between complementary nitrogenous bases.
3. In RNA, the nitrogenous base replaces thymine found in DNA.

1. Describe the key structural features of a DNA double helix, as shown in the diagram.
2. Explain the primary function of DNA in living organisms.
3. List three differences between DNA and RNA.
1. All types of RNA are single-stranded.
True
False
2. Adenine always pairs with Guanine in a DNA molecule.
True
False
Match the term on the left with its description on the right.
1. Deoxyribose
a. The process of making an RNA copy of a gene sequence
2. Uracil
b. Sugar found in DNA
3. Transcription
c. Nitrogenous base found only in RNA