DNA Replication Worksheet
A Grade 12 Biology worksheet on DNA replication, covering key enzymes, processes, and structures.
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DNA Replication Worksheet
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Read each question carefully and answer to the best of your knowledge. Use complete sentences where appropriate.
1. Which enzyme is responsible for unwinding the DNA double helix during replication?
DNA Polymerase
Helicase
Ligase
Primase
2. Okazaki fragments are found on which strand during DNA replication?
Leading strand
Lagging strand
Both leading and lagging strands
Neither strand
3. DNA replication is described as , meaning each new DNA molecule consists of one original strand and one newly synthesized strand.
4. The enzyme adds complementary nucleotides to the growing DNA strand.
5. DNA replication begins at a specific site called the origin of replication.
True
False
6. DNA ligase is responsible for removing RNA primers.
True
False
7. Describe the role of primase in DNA replication.
8. Explain why DNA replication is considered semi-conservative.
9. Label the following components on the DNA replication fork diagram:

a. Leading Strand
b. Lagging Strand
c. Helicase
d. DNA Polymerase
e. RNA Primer
f. Okazaki Fragment