Reconstitution Calculation Worksheet
Practice reconstitution calculations for Grade 6 math students, focusing on understanding concentration, volume, and dosage.
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Reconstitution Calculation Practice
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Read each question carefully and show your work for all calculations. Remember to include units in your answers.
1. Reconstitution is the process of adding a liquid (diluent) to a powdered substance to create a .
2. The amount of drug in a given volume of solution is called its .
3. If you have 100 mg of medication in 5 mL of solution, the concentration is mg/mL.
1. A vial contains 250 mg of powdered medication. If you add 5 mL of sterile water, what is the concentration of the reconstituted solution in mg/mL?

2. You need to administer 75 mg of a medication. The reconstituted solution has a concentration of 50 mg/mL. How many milliliters of the solution should you give?
1. A medication vial contains 1000 mg of powder. The instructions say to reconstitute with 2 mL of diluent to get a concentration of 500 mg/mL. What is the total volume of the reconstituted solution?
1 mL
2 mL
3 mL
4 mL
2. If a doctor orders 200 mg of a medication, and the available concentration is 100 mg/5 mL, how much volume should be administered?
5 mL
10 mL
15 mL
20 mL
1. Increasing the amount of diluent will decrease the concentration of the reconstituted solution.
True
False
2. If a medication is supplied as 500 mg per vial, and you want a concentration of 100 mg/mL, you should add 5 mL of diluent.
True
False
A patient needs 300 mg of a medication. The medication comes in a vial containing 600 mg of powder. The instructions state to reconstitute to a concentration of 200 mg/mL. How much diluent should be added to the vial, and what volume of the reconstituted solution should be administered to the patient?