Reconstitution Calculation Worksheet

Reconstitution Calculation Practice

Read each problem carefully and calculate the correct reconstitution. Show your work for full credit.

1. A medication comes in a vial with 500 mg of powder. The instructions state to reconstitute with 2.5 mL of sterile water to achieve a concentration of 200 mg/mL. How much total volume will the reconstituted solution be?

2. You need to administer 75 mg of a drug. The reconstituted solution has a concentration of 25 mg/mL. How many milliliters should you administer?

3. If a 1 gram vial of medication is reconstituted with 5 mL of diluent, the resulting concentration is   mg/mL.

4. To prepare a 10 mg/mL solution from a 200 mg vial, you would add   mL of diluent.

5. A medication vial contains 100 mg of powder. Reconstitution instructions suggest adding 4 mL of sterile water. What is the concentration of the reconstituted solution?

6. A patient requires a 50 mg dose of a medication. The available concentration after reconstitution is 12.5 mg/mL. What volume should be drawn up for injection?

7. Reconstitution always involves adding a liquid to a powder.

8. The final volume of a reconstituted solution is always equal to the volume of the diluent added.