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DNA Replication Worksheet

Explore the process of DNA replication, including key enzymes, steps, and its importance in heredity.

Grade 9 Science BiologyReplication
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Multiple ChoiceFill in the BlanksShort AnswerCustomTrue / FalseWord Bank

Standards

HS-LS1-1

Topics

BiologyDNAReplicationGeneticsScience
8 sections · Free to use · Printable
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DNA Replication Worksheet

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Read each question carefully and answer to the best of your ability. Refer to your notes or textbook if needed.

1. Which enzyme is responsible for unwinding the DNA double helix during replication?

a

DNA ligase

b

DNA polymerase

c

Helicase

d

Primase

2. What is the main function of DNA replication?

a

To produce RNA

b

To synthesize proteins

c

To create an identical copy of DNA

d

To break down DNA

3. DNA replication is described as  , meaning each new DNA molecule consists of one original strand and one newly synthesized strand.

4. The enzyme that adds new nucleotides to the growing DNA strand is  .

5. The short segments of DNA synthesized on the lagging strand are called   fragments.

6. Briefly explain the role of DNA helicase and DNA ligase in DNA replication.

7. Observe the diagram of a DNA replication fork below and answer the following questions.

DNA Replication Fork

a) Identify the leading strand and the lagging strand in the diagram.

b) In which direction does DNA polymerase synthesize new DNA strands?

8. Okazaki fragments are found on the leading strand during DNA replication.

T

True

F

False

Use the words below to complete the sentences.

semiconservative
replication fork
primase
nucleotides

9. The Y-shaped region where DNA strands are separated is called the  .

10. DNA polymerase adds complementary   to the template strand.